TABLE 9.

Comparative protection stimulated by EDIM particles in BALB/c and μMT mice^a

Immunogen	LT	Rotavirus shedding (% antigen shed vs mock-immunized mice)		Pb
		BALB/c	μMT
tl EDIM	−	0.0	22.6	<0.001
tl EDIM	+	0.0	0.5	NS
dl EDIM	−	4.8	23.1	<0.001
dl EDIM	+	0.6	0.2	NS

^aMice (eight animals per group for BALB/c and six animals per group for μMt) were administered two doses (10 μg/dose) of EDIM particles and challenged with EDIM 4 weeks after the second immunization. Shedding was measured during the 7 days after challenge. 

^bSignificance of differences between mice groups. NS, not significant.