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. 2023 Aug 16;23:170. doi: 10.1186/s12935-023-03010-9

Fig. 4.

Fig. 4

Role of miRNAs in regulation of CDDP mediated apoptosis in head and neck tumor cells. MiR-483-5p suppressed mitochondrial fission and CDDP sensitivity via FIS1 targeting in TSCC cells. MiR-196a modulated cell proliferation and apoptosis via targeting ING5. There were miR-125 up regulations in CDDP-resistant NPC tissues in comparison with normal tissues which were associated with p53 targeting. MiR-125a promoted CDDP-induced apoptosis through HAX1 targeting in laryngeal cancer stem cells. (Created with BioRender.com)