Table 1.
Demographic characteristics and sarcopenia parameters of patients with PD and HC group
| Variable | HC(n = 38) | PD(n = 123) | t/x2/z | P-Value |
|---|---|---|---|---|
| Age, y | 67.03 ± 10.89 | 65.73 ± 9.36 | 0.716 | 0.475 |
| Sarcopenia, n(%) | 4(10.5) | 33(26.8) | 0.046 | |
| Low muscle mass, n(%) | 4(10.5) | 33(26.8) | 0.046 | |
| Low muscle strength, n(%) | 14(36.8) | 48(39.0) | 0.058 | 0.809 |
| 6 m GS ≥ 6 s, n(%) | 22(57.9) | 101(82.1) | 9.444 | 0.002 |
| Education,y | 6.5(5,9) | 7(4,9) | -0.292 | 0.770 |
| Male, n(%) | 23(60.5) | 56(45.5) | 2.613 | 0.106 |
| Hypertension, n(%) | 9(23.7) | 34(27.7) | 0.232 | 0.630 |
| Type 2 diabetes, n(%) | 5(13.2) | 13(10.6) | 0.196 | 0.658 |
| Smoker, n(%) | 6(15.8) | 24(19.5) | 0.265 | 0.606 |
| Alcohol user, n(%) | 7(18.4) | 21(17.1) | 0.037 | 0.848 |
| Tea or coffee user, n(%) | 10(26.3) | 33(26.8) | 0.004 | 0.950 |
| state of nutrition | 2.076 | 0.150 | ||
| No risk of malnutrition, n(%) | 23(60.5) | 58(47.2) | ||
| Risk of malnutrition, n(%) | 15(39.5) | 65(52.8) | ||
| BMI (kg/m2) | 25.19 ± 2.58 | 23.64 ± 3.32 | 2.638 | 0.009 |
| ASM (kg/m2) | 7.24(6.57,7.86) | 6.83(5.91,7.70) | -1.178 | 0.075 |
| Grip strength (kg) | 25.35(20.65,33.6) | 22.60(18.05,30.55) | -2.307 | 0.021 |
| 6 m GS (s) | 6.02(5.36,6.83) | 7.26(6.41,8.48) | -4.459 | < 0.001 |
Values in bold are significant at P < 0.05
Data were expressed as n (%), mean ± SD, median (interquartile range). P values are from Student’s t-test or the Mann–Whitney U-test or Chi-square tests or Fisher’s exact test
Abbreviations: PD Parkinson's disease, HC healthy controls, BMI body mass index, ASM appendicular skeletal mass, 6 m GS 6-m gait speed