TABLE 2.
Transformation by recombinant EBV with wild-type or mutant BARF1 genea
| Mutant BARF1 cell line |
No. of transformants/ 104 cells | Wild-type BARF1 cell line |
No. of transformants/ 104 cells | |
|---|---|---|---|---|
| 3A1 | 1.9 | 5B8 | 1.9 | |
| 3A3 | 1.8 | 12A1 | 1.9 | |
| 3A4 | 1.8 | 12A2 | 0.9 | |
| 3B1 | 1.9 | 12A3 | 1.4 | |
| 3B2 | 1.9 | 12B2 | 1.9 | |
| 3B3 | 1.9 | 12B3 | 1.9 | |
| 6 | 1.3 | 12B4 | 1.9 | |
| 9A1 | 1.9 | 12B5 | 0.5 | |
| Median | 1.9 | Median | 1.9 |
a
5 × 105 cells from each cell line were treated with PMA to induce replication, lethally irradiated, and cocultivated with B cells in 96-well plates. Six weeks after plating, the number of wells containing transformed cells was counted and the number of transformants per 104 irradiated cells was calculated.