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Endomyocardial Biopsy Specimens Demonstrating Transthyretin Amyloid
Photomicrographs of hematoxylin and eosin-stained sections of myocardium (A, B) showing amyloid deposits (arrows) characterized by acellular deposits of pink extracellular matrix material that are devoid of cells and exhibit cracking. These deposits stain light red/orange by Congo Red stain (C). Immunohistochemical staining (brown chromogen) shows intense reactivity with antibodies against transthyretin (D).
