FIG. 3.

Kinetics of RNA synthesis by HCV NS5B with full-length HCV RNA as a template. (A) In vitro RdRp reactions were terminated at the time points indicated above the gel in minutes and analyzed on a 1% agarose gel after the products had been heat denatured. (B) Longer RdRp reactions up to 5 h. Exposure time was controlled to visualize the discrete bands for late time points (2, 3, 4, and 5 h). Arrowheads indicate the positions of the RNA template.