Dual-functional antibacterial peptidomimetics possessing antibacterial and immunomodulatory properties.

Compounds	MIC	Immunomodulatory activity	Ref.
ASAM-10 (12)	0.9–7.8a	Lowers TNF-α, IL-6, IL-8, and IL-1β	112
Compound 2 (13)	3.1–6.2a	Lowers TNF-α	113
NCK-10 (14)	4.1–5.7b	Lowers TNF-α and IL-6	120
SMAMP 3 (15)	3.13–12.5a	Lowers TNF-α	121
HDAMP-1 (16)	4.3b	Lowers TNF-α and NO	122
YL-36 (17)	1–5b	Lowers NO	123
Compound 3 (18)	0.6–2.4b	Lowers TNF-α and NF-κB	124
20 : 80 Bu : DM (19)	3.13–25a	Modulates MCP-1, TNF-α, IL-1β, IL-10, and IL-1RA levels in a concentration dependent manner	126
QCybuAP and Qn-prAP (20)	8–16a	Lowers TNF-α and IL-6	131
LPEI (21)	17.8a	Lowers TNF-α and IL-6	132

^aμg mL⁻¹.

^bμM.