Table 5.
Vaccine Efficacy Against S. aureus Colonization Detected by Positive Nasal, Oral, and Nasal/Oral Culture by 56 Days Post Vaccination – Baseline S. aureus Nasal/Oral Colonization Negative Subjects
| Endpoint at 56 days post-vaccination | Vaccine Efficacya (95% CI) | p-valueb |
|---|---|---|
| Positive nasal culture | 12.1% (−31.6%, 41.3%) | 0.31 |
| Positive oral culture | 2.4% (−50.9%, 36.9%) | 0.52 |
| Positive nasal/oral culture | 6.2% (−37.6%, 36.1%) | 0.43 |
CI: confidence interval
Vaccine efficacy calculated using unadjusted relative risk ratio (VE: 1 – Relative Risk)
p value from Fisher’s exact 1-tailed test