Fig. 2.

Faecal microbiome variations in patients with adult-onset T1D and patients with T2D. Alpha and beta diversity comparison of bacteria (A, B), viruses (C, D) and fungi (E, F) among patients with adult-onset T1D, patients with T2D and HCs. (G, H) Percentage of bacterial community abundance at phylum and genus levels; phyla or genera with a relative abundance <1% in each sample are merged into others. Box plots show median ± quartiles, and the whiskers extend from the hinge to the largest or smallest value no further than 1.5 folds of the inter-quartile range. ∗P < 0.05, Abbreviations: HCs, healthy controls; T1D, type 1 diabetes; T2D, type 2 diabetes; PCoA, principal coordinated analysis; PERMANOVA, permutational multivariate analysis of variance.