Fig. 7.

Disease classification based on the signatures of gut microbiome and metabolome. Random forest classifiers composed of bacteria, metabolites and their combination were constructed to discriminate patients with adult-onset T1D from HCs (A) and from patients with T2D (B) in the discovery set. Validation of random forest classifiers composed of bacteria, metabolites and their combination in discriminating patients with adult-onset T1D from HCs (C) and from patients with T2D (D). Abbreviations: HCs, healthy controls; T1D, type 1 diabetes; T2D, type 2 diabetes; AUC, area under the curve.