Table 2.
Gene ID | Mean CTR (CPM) | Mean HFpEF (CPM) | FDR p value |
---|---|---|---|
IL1B | 0.3851 | 0.5376 | 0.7868 |
IL6 | 0.6835 | 0.9751 | 0.6745 |
IL7 | 0.3129 | 0.2797 | 0.9760 |
IL10 | 0.2665 | 0.1869 | 0.8322 |
IL12A | 0.2578 | 0.2131 | 0.8643 |
IL15 | 4.9894 | 4.9001 | 0.9947 |
IL16 | 15.0293 | 12.0188 | 0.5825 |
IL17D | 0.3983 | 0.3874 | 0.9851 |
IL18 | 2.5176 | 1.2784 | 0.4690 |
IL23A | 0.0706 | 0.0929 | 0.8647 |
IL32 | 14.0823 | 13.5219 | 0.9748 |
IL33 | 8.5082 | 7.8487 | 0.8757 |
IL34 | 1.0356 | 1.3530 | 0.5625 |
CCL2 | 4.9154 | 4.5330 | 0.9051 |
CCL3 | 0.3286 | 0.3006 | 0.9587 |
CCL3L1 | 0.1334 | 0.1286 | 0.9845 |
CCL4 | 0.1920 | 0.1893 | 0.9941 |
CCL4L2 | 0.1179 | 0.1471 | 0.9150 |
CCL5 | 1.2513 | 1.4761 | 0.7694 |
CCL8 | 0.2299 | 0.3275 | 0.7048 |
CCL11 | 0.8289 | 1.1145 | 0.6579 |
CCL13 | 0.2318 | 0.0882 | 0.6244 |
CCL14 | 0.2098 | 0.3059 | 0.7627 |
CCL16 | 0.0691 | 0.0713 | 0.9922 |
CCL17 | 0.0374 | 0.0244 | 0.8693 |
CCL18 | 0.2356 | 0.1688 | 0.9228 |
CCL19 | 0.2033 | 0.1634 | 0.9648 |
CCL20 | 0.0276 | 0.0071 | 0.8555 |
CCL21 | 6.7012 | 5.1999 | 0.8132 |
CCL22 | 0.0659 | 0.0643 | 0.9964 |
CCL23 | 0.0285 | 0.0178 | 0.9785 |
CCL24 | 0.2568 | 0.0618 | 0.4358 |
CCL26 | 0.0090 | 0.0514 | 0.5650 |
CCL28 | 0.4620 | 0.3277 | 0.7164 |
CXCL1 | 1.2774 | 0.9655 | 0.7194 |
CXCL2 | 21.7835 | 19.2811 | 0.9046 |
CXCL3 | 0.7977 | 0.5684 | 0.6745 |
CXCL5 | 0.0679 | 0.0868 | 0.9156 |
CXCL6 | 0.0953 | 0.0938 | 0.9845 |
CXCL8 | 0.2114 | 0.4075 | 0.6745 |
CXCL9 | 0.9959 | 1.3412 | 0.6745 |
CXCL10 | 0.2631 | 0.5891 | 0.2150 |
CXCL11 | 0.0286 | 0.1430 | 0.3613 |
CXCL12 | 70.0774 | 70.5659 | 0.8887 |
CXCL14 | 2.0714 | 1.1787 | 0.5671 |
CXCL16 | 2.1066 | 2.0347 | 0.9845 |
CXCL17 | 0.0146 | 0.0109 | 0.9852 |
CSF1 | 15.0473 | 12.7733 | 0.5671 |
CSF3 | 0.0881 | 0.0261 | 0.6745 |
Table 2. List of pro-inflammatory mediators in control and HFpEF myocardium. The mean CPM values for control and HFpEF samples and p values are provided. CPM, counts per million; IL, interleukin; CCL, C-C motif chemokine ligand; CXCL, C-X-C motif chemokine ligand; CSF, colony stimulating factor.