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. 2022 Jul 31;3:100024. doi: 10.1016/j.bjao.2022.100024

Table 2.

Anaesthesiology protocol and assessment by the Analgesia Nociception Index (ANI) and videopupillometry. ∗Median [25th–75th percentiles], n (%).

Drugs n=89∗
Acetaminophen 89 (100%)
Ketoprofen 89 (100%)
Ketamine 89 (100%)
Alfentanil 89 (100%)
 Alfentanil dose 20 [19–21] μg kg−1
 Alfentanil second injection 31 (35%)
 Alfentanil second injection dose 10 [8–11] μg kg−1
 Time between ANI and videopupillometer assessments and last alfentanil injection 24 [17–34] min
 Time between ANI and videopupillometer assessments and alfentanil injection in patients without second injection 29 [23–38] min
 Time between ANI and videopupillometer assessments and second alfentanil injection
16 [11–20] min
Total anaesthesia duration
30 [24–36] min
ANI assessment
 Patients with ANI assessment 81 (91%)
 Mean ANI at 4 min 55 [48–66]
 Instant ANI at 4 min 59 [49–70]
Pupillometry assessment
 Patients with videopupillometry assessment 87 (98%)
 Pupillary Pain Index score at 4 min 2 [1–2]
 Pupillary diameter variations at 4 min 6 [2–10]%