Kaplan-Meier estimates of rPFS. (A) rPFS of the subgroup of patients with BRCA1/2 alterations as assessed by blinded independent central review. (B) rPFS of the overall HRR+ cohort as assessed by blinded independent central review. (C) Prespecified sensitivity analysis of rPFS of patients with BRCA1/2 alterations by investigator assessment. (D) rPFS of the overall HRR+ cohort by investigator assessment. AAP, abiraterone acetate plus prednisone; HR, hazard ratio; HRR, homologous recombination repair; NIRA, niraparib; PBO, placebo; PFS, progression-free survival; rPFS, radiographic progression-free survival.