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. 2023 Aug 1;14:1178339. doi: 10.3389/fphys.2023.1178339

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Copyright © 2023 Carey, Hotvedt, Mummy, Lee, Denlinger, Schiebler, Sorkness, Jarjour, Hatt, Galban and Fain.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Examples of severe asthmatics where PRM and HP gas MRI are discordant. The most common discordant pattern is (A,B) HP 3He MRI ventilation > fSAD with whole lung VDP of 18.4% and PRMfSAD of 5.8%, and the least common is in (C,D) HP 3He MRI ventilation << fSAD with a whole lung VDP of 6.3% and PRMfSAD of 23.7%.