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. 2023 Aug 16;3(8):e0001982. doi: 10.1371/journal.pgph.0001982

Table 1. Comparison of cervical cancer screening methods [2].

Carcinogenic HPV testing Cytology (Pap) Visual Inspection with Acetic Acid (VIA)
Brief definition Molecular testing for carcinogenic HPV, which is the etiologic cause of cervical cancer Microscopic evaluation of cervical cells to look for abnormalities associated with cervical cancer Visual inspection of the cervix to look for lesions, which turn white in the presence of 5% acetic acid
General testing logistics Sample is self-collected or provider-collected during a pelvic exam and sent to a laboratory for testing Cells are collected from the cervix by a provider during a pelvic exam and sent to a laboratory for evaluation Provider applies dilute acetic acid during a pelvic exam and evaluates the cervix with adequate illumination
Infrastructure required Medium High Low
Sensitivity High Medium Variable
Specificity Medium High Variable