Table 1. Comparison of cervical cancer screening methods [2].
Carcinogenic HPV testing | Cytology (Pap) | Visual Inspection with Acetic Acid (VIA) | |
---|---|---|---|
Brief definition | Molecular testing for carcinogenic HPV, which is the etiologic cause of cervical cancer | Microscopic evaluation of cervical cells to look for abnormalities associated with cervical cancer | Visual inspection of the cervix to look for lesions, which turn white in the presence of 5% acetic acid |
General testing logistics | Sample is self-collected or provider-collected during a pelvic exam and sent to a laboratory for testing | Cells are collected from the cervix by a provider during a pelvic exam and sent to a laboratory for evaluation | Provider applies dilute acetic acid during a pelvic exam and evaluates the cervix with adequate illumination |
Infrastructure required | Medium | High | Low |
Sensitivity | High | Medium | Variable |
Specificity | Medium | High | Variable |