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. 2023 Jul 20;8(30):26837–26849. doi: 10.1021/acsomega.3c01462

Table 2. ADME Prediction of Oxadiazole Analogues (6aj).

s. no. compound % ABS volume TPSA NROTB HBA HBD Log P (iLOGP) MW BBB permeation GI absorption Lipinski’s violations
1 6a 91.42 232.24 50.95 3 7 1 2.73 309.22 yes high 0
2 6b 91.42 240.85 50.95 3 6 1 2.90 325.67 no high 0
3 6c 91.42 245.20 50.95 3 6 1 2.99 370.12 no high 0
4 6d 91.42 243.87 50.95 3 6 1 2.88 305.25 yes high 0
5 6e 88.24 252.86 60.18 4 7 1 2.93 321.25 yes high 0
6 6f 91.42 240.85 50.95 3 6 1 3.01 325.67 no high 0
7 6g 88.24 252.86 60.18 4 7 1 3.11 321.25 yes high 0
8 6h 91.42 260.43 50.95 3 6 1 3.23 319.28 yes high 0
9 6i 91.42 260.43 50.95 3 6 1 3.23 319.28 yes high 0
10 6j 91.42 245.78 50.95 3 7 1 2.85 343.66 no high 0