Table 3. Prediction of Toxicities of Oxadiazole Analogues (6a–j).
| s. no. | compound | hepatotoxicity | carcinogenicity | immunotoxicity | mutagenicity | cytotoxicity | LD50 (mg/Kg) | class |
|---|---|---|---|---|---|---|---|---|
| 1 | 6a | + | + | – | – | – | 550 | IV |
| 2 | 6b | + | – | – | – | – | 550 | IV |
| 3 | 6c | + | + | – | – | – | 550 | IV |
| 4 | 6d | + | + | – | – | – | 550 | IV |
| 5 | 6e | + | – | – | – | – | 550 | IV |
| 6 | 6f | + | – | – | – | – | 550 | IV |
| 7 | 6g | + | – | – | – | – | 1087 | IV |
| 8 | 6h | + | + | – | – | – | 550 | IV |
| 9 | 6i | + | + | – | – | – | 550 | IV |
| 10 | 6j | + | – | – | – | – | 550 | IV |