Table 4.
Distribution of Immunohistochemical Subtypes of Pituitary Adenomas by Age, Sex and Biopsy Size in Enugu [2008–2017].
| Variable | Null cell n = 44%) |
PRL only n = 27%) |
GH only n = 3%) |
TSH only n = 2%) |
ACTH only n = 1%) |
FSH only n = 7%) |
LH only n = 13%) |
Plurihormonal n = 3%) |
Total |
|---|---|---|---|---|---|---|---|---|---|
| Age groups (Years) | |||||||||
| <20 | - | - | - | - | - | - | - | - | 0.0 |
| 20–29 | 6 (13.6) | 5 (18.5) | - | - | - | - | - | - | 11.0 |
| 30–39 | 13 (29.6) | 5 (18.5) | 2 (66.7) | - | 1(100.0) | 3(42.8) | 4 (30.8) | 1(33.3) | 29.0 |
| 40–49 | 13(29.6) | 9 (33.3) | 1 (33.3) | 1 (50.0) | - | 1(14.3) | 3(23.0) | - | 28.0 |
| 50–59 | 5(11.3) | 6 (22.2) | - | 1 (50.0) | - | 1(14.3) | 4(30.8) | 1(33.3) | 18.0 |
| 60–69 | 6(13.6) | 2 (7.4) | - | - | - | 1(14.3) | 2(15.4) | 1(33.3) | 12.0 |
| ≥70 | 1 (2.3) | - | - | - | - | 1(14.3) | - | - | 2.0 |
| Sex | |||||||||
| Male | 25(56.8) | 16 (59.3) | 1 (33.3) | 2 (100.0) | 1(100.0) | 2(28.6) | 7 (53.8) | 1(33.3) | 55.0 |
| Female | 19(43.2) | 11 (40.7) | 2 (66.7) | - | - | 5(71.4) | 6(46.2) | 2(66.6) | 45.0 |
| Biopsy size (cm) | |||||||||
| <1 | 4 (9.1) | 5 (18.5) | - | - | - | - | 2 (15.4) | - | 11 |
| 1–4 | 39(88.6) | 21 (77.8) | 3 (100.0) | 2 (100.0) | 1(100.0) | 7(100.0) | 11(84.6) | 3(100.0) | |
| >4 | 1(2.3) | 1 (3.7) | - | - | - | - | - | - | 2 |
Note: NB: PRL – prolactin, LH – luteinizing hormone, FSH – follicle stimulating hormone, GH – growth hormone, TSH – thyroid stimulating hormone, ACTH – adrenocorticotrophic hormone.