Summary of findings 5. Bispectral index (BIS)‐guided anaesthesia versus BIS‐blinded anaesthesia/clinical judgement for preventing delirium in hospitalised non‐ICU patients.
| Bispectral index (BIS)‐guided anaesthesia versus BIS‐blinded anaesthesia/clinical judgement for preventing delirium in hospitalised non‐ICU patients | ||||||
| Intervention: Bispectral index (BIS)‐guided anaesthesia | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | № of participants (studies) | Quality of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| BIS‐blinded/clinical judgement | BIS‐guided | |||||
|
Incidence of delirium CAM, DSM‐IV Follow‐up: daily after surgery until discharge; twice daily from postoperative day 1 to 7 |
226 per 10001 | 160 per 1000 (135 to 192) | RR 0.71 (0.60 to 0.85) | 2057 (2 studies) | ⊕⊕⊕⊝ moderate2 | |
| Duration of delirium ‐ not measured | N/A | N/A | N/A | N/A | ||
| Severity of delirium ‐ not measured | N/A | N/A | N/A | N/A | ||
|
Length of admission Days |
The mean length of admission in the control groups ranged from 7 to 15.7 days |
The mean length of admission in the intervention group was 0.94 days shorter (0.43 days shorter to 1.45 days shorter) | ‐ | 2057 (2 studies) | ⊕⊕⊕⊝ moderate2 | |
| Return to independent living ‐ not measured | N/A | N/A | N/A | N/A | ||
| In‐hospital mortality ‐ not measured | N/A | N/A | N/A | N/A | ||
| *The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio; OR: Odds ratio; | ||||||
| GRADE Working Group grades of evidence High quality: We are very confident that the true effect lies close to that of the estimate of the effect Moderate quality: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low quality: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect Very low quality: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect | ||||||
1 The assumed risk is the risk in the control group (BIS‐blinded/clinical judgement) 2 Downgraded due to risk of bias