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. 2016 Mar 11;2016(3):CD005563. doi: 10.1002/14651858.CD005563.pub3

Comparison 10. Intravenous parecoxib sodium analgesia versus Morphine and Saline.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Incident delirium 1 80 Risk Ratio (M‐H, Random, 95% CI) 0.5 [0.26, 0.98]
2 Length of admission 1 80 Mean Difference (IV, Random, 95% CI) ‐0.90 [‐1.58, ‐0.22]
3 Postoperative cognitive dysfunction at 3 days 1 80 Risk Ratio (M‐H, Random, 95% CI) 0.47 [0.21, 1.02]
4 Postoperative cognitive dysfunction at 1 week 1 80 Risk Ratio (M‐H, Random, 95% CI) 0.38 [0.15, 0.98]
5 Postoperative cognitive dysfunction at 3 months 1 80 Risk Ratio (M‐H, Random, 95% CI) 0.30 [0.09, 1.01]
6 Postoperative cognitive dysfunction at 6 months 1 80 Risk Ratio (M‐H, Random, 95% CI) 0.14 [0.02, 1.11]