Avidan 2009.

Trial name or title	BAG‐RECALL Study: BIS or anesthesia gas to reduce explicit recall
Methods	Phase IV double‐blind multi‐centre randomised controlled trial
Participants	Patients aged over 18 undergoing surgery assessed as high risk for awareness requiring general anaesthesia
Interventions	Group 1: Bispectral index‐guided anaesthesia (target range 40‐60) Group 2: End‐tidal anaesthetic gas‐guided anaesthesia (target range 0.7‐1.3 age‐adjusted minimum alveolar concentration)
Outcomes	Primary outcome: Awareness with explicit recall during surgical and anaesthetic periods Secondary outcomes: postoperative delirium, postoperative mortality, psychological symptoms, postoperative pain
Starting date	March 2008
Contact information	Michael Avidan avidanm@wustl.edu
Notes	ClinicalTrials.gov identifier: NCT00682825 Completed December 2010. Published N Engl J Med 2011 Aug 18;365(7):591‐601 but delirium outcome not reported yet.