Coburn 2012.

Trial name or title	An international, multi‐centre randomised controlled trial evaluating the effect of xenon on post‐operative delirium in elderly patients undergoing hip fracture surgery
Methods	Multi‐centre double‐blind randomised controlled trial
Participants	Patients aged 75 and over with hip fracture and surgery planned within 48 hours and able to provide informed consent
Interventions	Intervention: Xenon 60% (1 MAC) in oxygen (FiO2 0.35‐0.45) Control: Sevoflurane 1.1‐1.4%(1 MAC) in oxygen (FiO2 = 0.35‐0.45) and medical air
Outcomes	Primary outcome: Postoperative delirium (CAM) within four days post‐surgery Secondary outcomes: Postoperative delirium (CAM) from day 5 postoperatively until discharge, sequential organ failure assessment from day 1 to day 4 post‐surgery, recovery parameters, safety and health economic parameters
Starting date	September 2010
Contact information	Steffen Rex steffen.rex@uzleuven.be
Notes	ClinicalTrials.gov identifier NCT01199276 Estimated completion date December 2013