Table 4. Hazard ratios of mortality for all causes, except for accidents and cancer of all sites by blood levels of SOD activity and Zn/Cu ratio, and serum levels of SOD activity and TBARS among the follow-up residents.
Components | Quartile | No. of subjects |
Person years |
No. of death |
Mortality rates |
Model 1 | p | Model 2 | p |
H.R.(95%C.I.) | H.R.(95%C.I.) | ||||||||
Blood SOD activity (unit/ml) |
Q1 (low) | 115 | 2010.0 | 15 | 7.46 | 1.20 (0.56-2.58) | 0.64 | 1.35 (0.64-2.97) | 0.46 |
Q2 | 123 | 2092.5 | 20 | 9.56 | 1.80 (0.87-3.70) | 0.11 | 1.61 (0.77-3.35) | 0.21 | |
Q3 | 104 | 1812.5 | 11 | 6.07 | 1.48 (0.64-3.39) | 0.36 | 1.48 (0.63-3.45) | 0.37 | |
Q4 (high) | 117 | 2052.0 | 12 | 5.85 | 1.00 | 1.00 | |||
trend p=0.40 | trend p=0.63 | ||||||||
| |||||||||
Blood Zn/Cu ratio |
Q1 (low) | 108 | 1874.0 | 12 | 6.40 | 1.99 (0.87-4.56) | 0.10 | 1.95 (0.85-4.48) | 0.12 |
Q2 | 120 | 2056.5 | 18 | 8.75 | 1.98 (0.93-4.26) | 0.08 | 2.23 (1.03-4.79)* | 0.04 | |
Q3 | 116 | 1987.0 | 17 | 8.56 | 1.71 (0.80-3.67) | 0.17 | 1.94 (0.90-4.21) | 0.09 | |
Q4 (high) | 115 | 2049.5 | 11 | 5.37 | 1.00 | 1.00 | |||
trend p=0.28 | trend p=0.20 | ||||||||
| |||||||||
Serum SOD activity (unit/ml) |
Q1 (low) | 139 | 2429.5 | 17 | 7.00 | 1.67 (0.80-3.49) | 0.14 | 1.64 (0.76-3.55) | 0.21 |
Q2 | 103 | 1738.0 | 19 | 10.93 | 2.15 (1.04-4.42)* | 0.04 | 2.07 (0.99-4.31) | 0.05 | |
Q3 | 106 | 1857.0 | 9 | 4.85 | 1.04 (0.44-2.48) | 0.93 | 0.84 (0.36-2.14) | 0.78 | |
Q4 (high) | 111 | 1942.5 | 13 | 6.69 | 1.00 | 1.00 | |||
trend p=0.12 | trend p=0.09 | ||||||||
| |||||||||
Serum TBARS level (nmol/ml) |
Q1 (low) | 130 | 2274.0 | 13 | 5.72 | 0.88 (0.41-1.92) | 0.76 | 0.74 (0.33-1.67) | 0.47 |
Q2 | 106 | 1854.5 | 12 | 6.47 | 1.19 (0.54-2.64) | 0.66 | 1.03 (0.45-2.34) | 0.94 | |
Q3 | 123 | 2086.5 | 20 | 9.59 | 1.11 (0.55-2.25) | 0.77 | 1.18 (0.58-2.42) | 0.65 | |
Q4 (high) | 100 | 1752.0 | 13 | 7.42 | 1.00 | 1.00 | |||
trend p=0.88 | trend p=0.65 |
Hazard ratios (H.R.) and 95% confidence intervals (95%C.I.) were calculated using Cox proportional hazard model (StatView statistical package, Power Macintosh), after adjusting for sex and age (Model 1), or after adjusting for sex, age, habits of smoking status and alcohol consumption, and BMI (Model 2).
* : p < 0.05.
Mortality rates = [No. of deaths/ person years] × 1000