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. 2023 Jul 3;3(8):931–937. doi: 10.1038/s43587-023-00441-x

Extended Data Fig. 2. Time course of serum klotho levels following treatment of two aged rhesus macaques.

Extended Data Fig. 2

Following Rhesus KL injection (s.c., 30 μg/kg), blood was collected at 4 h, 28 h and 52hrs (n = 8 samples from 2 monkeys, female, ages 22 and 24 years). Assuming peak concentration at 4 h, putative klotho half-life was 29.5 h with predicted elimination in 6.15 days.

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