Extended Data Fig. 4. Heatmaps of biological relatedness.

a, Heatmap showing pairwise outgroup f₃ statistics between all individuals from Gurgy (n = 94). Lighter colours indicate higher shared genetic affinity between individuals. Each sub-lineage forms a cluster, and the two bigger pedigrees are also visible (Supplementary Note 5, Supplementary Table 12). b, Heatmap showing pairwise outgroup f₃ statistics between all exogenous female individuals (n = 16). Three pairs show distant relatedness (GLN232B-GLN294, GLN288-GLN298, GLN242-GLN315), but are otherwise unrelated (Supplementary Note 5, Supplementary Table 12). c, Heatmap showing pairwise IBD sharing between individuals with more than 500,000 SNPs (n = 72). Different clusters of lighter colour reveal the extra-links between the different branches and pedigrees (Supplementary Notes 3 and 5, Supplementary Table 10). d, Heatmap showing pairwise IBD sharing between all exogenous female individuals with more than 500,000 SNPs (n = 12). The absence of relatedness between the exogenous female individuals is confirmed by the deeper resolution provided by IBD sharing analysis, with a single pair of females related in the third degree, as detected by the f₃ statistics (Supplementary Notes 3 and 5, Supplementary Table 10).