Table 7.

Research questions

PICO question	Consensus statement
Clinical targets	To develop outcome and quality of life measures for neonates and young infants on kidney replacement therapy, similarly to what is done with the SONG (Standardized Outcomes in Nephrology) initiative in older children and adults
Biochemical targets	To determine the targets for the main biomarkers in this age group in case of CKD, and notably PTH, 25(OH)D, and ALP
Nutritional specificities	Balance studies to determine the true Ca requirements in infants for optimal bone quality and without a risk of vascular calcifications. To determine if urinary calcium excretion in healthy infants and those with CKD can be used to evaluate optimal calcium intakes
Therapeutic specificities	Cinacalcet data in infants in a real-life setting CKD-MBD in preterm infants