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. 2023 Aug 16;14:4958. doi: 10.1038/s41467-023-40668-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a The shedding process of CTCs from the in vivo tumor site (middle) and lesions of CTCs in whole blood specimen during HP (left and right). b The assembling process of magnetic microgels and ZBVA hydrogel formation for CTC preservation and effortless retrieval. c The mechanism of CTC protection against HP lesions by using the microgel platform.