Table 3.
Diagnostic performance of several tests in pleural fluid.
| Test | CRS diagnosed TPE |
Sensitivity |
specificity |
AUC |
||
|---|---|---|---|---|---|---|
| Positive | Negative | %（95%CI） | %（95%CI） | %（95%CI） | ||
| Culture | 12.2 (6.3–20.8) | 100.0 (75.3–100.0) | 0.56 (0.46–0.66) | |||
| Positive | 11 | 0 | ||||
| Negative | 79 | 13 | ||||
| Xpert | 24.0 (16.0–33.2) | 100.0 (71.5–100.0) | 0.62 (0.52–0.71) | |||
| Positive | 24 | 0 | ||||
| Negative | 76 | 11 | ||||
| ADA≥35 (U/L) | 46.1 (37.2–55.1) | 100.0 (89.7–100.0) | 0.73 (0.66–0.80) | |||
| Positive | 59 | 0 | ||||
| Negative | 69 | 34 | ||||
| LAM | 47.7 (39.2–56.3) | 100.0 (89.7–100.0) | 0.74 (0.66–0.80) | |||
| Positive | 61 | 0 | ||||
| Negative | 67 | 34 | ||||
| LAM + ADA | 68.0 (59.1–75.9) | 100.0 (89.7–100.0) | 0.84 (0.77–0.89) | |||
| Positive | 87 | 0 | ||||
| Negative | 41 | 34 | ||||
TPE, tuberculous pleural effusion; LAM, lipoarabinomannan; ADA, adenosine deaminase; CI, confidence interval.