TABLE 2.

Locations of proteolytic cleavage sites of spumaviral Gag proteins

Virusa	p33–p5	p3.5–p1.5	p1.5–p29	p68–p3b
HFV	QHIR↓SVTG	DGVF↓PVTT	RIIN↓AILG	RAVN↓TVTQ
SFV-1	QHIR↓AVTG	EGVF↓PIPT	RVIN↓ALLG	RSVN↓TVTA
SFV-3	QHIR↓AVTG	EGVF↓MTTP	RVVN↓ALIG	RNVD↓TVTA
BFV	THIR↓AVIG	QGVY↓PVQD	RTVN↓ALTV	SAVH↓SVRL
FeFV	NHLR↓SVIG	EGVF↓PIVD	RRVN↓ALVA	AAVH↓TVKA
Consensus	XH(I/L)R↓(A/S)V(T/I)G	XGV(F/Y)↓(P/M)XXX	RX(I/V)N↓A(I/L)XX	XXVX↓(T/S)VXX

^aHFV, human FV; SFV, simian FV; BFV, bovine FV; FeFV, feline FV. 

^bThe p68/p3 cleavage has been reported previously (15). Conserved residues are boldfaced.