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. 2023 Aug 5;9(8):e18957. doi: 10.1016/j.heliyon.2023.e18957

Table 1.

List of biosensors for identifying respiratory infection biomarkers.

Disease Biosensor Target Probe Material Limit of detection References
Pneumonia Colorimetric assay DNA DNA Gold 1 pM [27]
Pneumonia DLS Procalcitonin Antibody Magnetic 0.03 pg/mL [30]
Pneumonia Colorimetric assay S. aureus Peptide Gold and magnets 7 CFU/mL [32]
Influenza LFA Influenza virus Aptamer and antibody Gold 2 × 106 virus particles [65]
Influenza Impedance sensor Matrix protein Antibody Diamond 1 pg/mL [34]
Influenza A Waveguide mode sensor Influenza A virus Aptamer Gold 8 × 103 PFU/mL [41]
Influenza LFA Capsid protein Antibody Gold 1:10,000 dilution [66]
Influenza A LOOP cDNA DNA [67]
Influenza B SPR Influenza B virus Aptamer Silica 7 ng/mL [38]
SARS CoV-19 Electrochemical sensor Spike protein Antibody Gold 1 pg/mL [68]
SARS-CoV-2 FET sensor Spike protein Antibody Graphene 1.6 × 101 PFU/mL [50]
COVID-19 Impedance spectroscopy Spike protein Antibody Diamond 189 fM [49]
RSV Cyclic voltammetry F protein Antibody Gold 1.1 × 103 PFU/mL [60]
RSV Cyclic voltammetry F protein Antibody Glossy carbon 2.85 × 106 PFU/mL [60]
RSV Fluorescence DNA DNA Gold 11.9 PFU [62]
RSV CARD RSV Antibody Gold 0.01 pg/mL [63]
Salmonella CRISPR DNA DNA Gold 1 CFU/mL [25]
S. typhimurium CRISPR DNA DNA Dyna beads 20 CFU/mL [69]
TB Colorimetric assay ESAT-6 Gold 1.25 pM [22]
TB Impedance 16 kDA HSP Antibody Gold 100 fM [18]
TB Electrochemical sensor Aptamer DNA Gold 100 CFU/mL [70]
Staphylococcus aureus CRISPR MecA gene Guide RNA Silver 10 fM [71]