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. 2023 Aug 9;31:63–86. doi: 10.1016/j.bioactmat.2023.08.001

Table 2.

Summary of encapsulation of core materials with the cell membrane from different cells.

Source cells Core materials Application Tumor cell type Size (nm) Ref.
Tumor cells CpG, αHSP70p, phosphate calcium Kill tumor cells and activate the innate NK cells and adaptive cytotoxic T cells immune response for tumor regression B16OVA 200 [147]
Macrophages Nano-gemcitabine System Promote the CD8+ T cells and NK cells infiltration in tumors and synergize anti-PD-L1 to restore their tumoricidal function for cancer immunotherapy 4T1, CT-26, PANC02 94 [148]
Red blood cells Perfluorohexane, glucose oxidase Exhaust glucose to produce the toxicity of H2O2 for killing tumor cells and re-educating M2-type TAMs into M1 type 4T1 190 [151]
NK cells TCPP, mPEG-PLGA Cause tumor cell death through photodynamic therapy and enhance the efficacy of anti-tumor immunity 4T1 80 ± 1.5 [152]
NK cells DOX Extend the circulation half-life and enhance tumor homing efficiency of nanomaterials for tumor chemotherapy and immunotherapy MCF-7 70 [153]
NK cells AIEdots Cross the BBB for high contrast tumor imaging and photothermal therapy of glioma U-87 MG 78 [154]
NK cells Hollow mesoporous silica loaded with AIPH and (TA)/Fe3+ Consume GSH and enhance free radical therapy HepG2 153.2 ± 16.2 [155]