Table 2.
Summary of encapsulation of core materials with the cell membrane from different cells.
| Source cells | Core materials | Application | Tumor cell type | Size (nm) | Ref. |
|---|---|---|---|---|---|
| Tumor cells | CpG, αHSP70p, phosphate calcium | Kill tumor cells and activate the innate NK cells and adaptive cytotoxic T cells immune response for tumor regression | B16OVA | 200 | [147] |
| Macrophages | Nano-gemcitabine System | Promote the CD8+ T cells and NK cells infiltration in tumors and synergize anti-PD-L1 to restore their tumoricidal function for cancer immunotherapy | 4T1, CT-26, PANC02 | 94 | [148] |
| Red blood cells | Perfluorohexane, glucose oxidase | Exhaust glucose to produce the toxicity of H2O2 for killing tumor cells and re-educating M2-type TAMs into M1 type | 4T1 | 190 | [151] |
| NK cells | TCPP, mPEG-PLGA | Cause tumor cell death through photodynamic therapy and enhance the efficacy of anti-tumor immunity | 4T1 | 80 ± 1.5 | [152] |
| NK cells | DOX | Extend the circulation half-life and enhance tumor homing efficiency of nanomaterials for tumor chemotherapy and immunotherapy | MCF-7 | 70 | [153] |
| NK cells | AIEdots | Cross the BBB for high contrast tumor imaging and photothermal therapy of glioma | U-87 MG | 78 | [154] |
| NK cells | Hollow mesoporous silica loaded with AIPH and (TA)/Fe3+ | Consume GSH and enhance free radical therapy | HepG2 | 153.2 ± 16.2 | [155] |