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. 2023 Jun 28;299(8):104981. doi: 10.1016/j.jbc.2023.104981

Table 1.

Surface plasmon resonance affinity measurements for wild-type (WT) CD8αα and the CD8αα variants S53G and S53N versus SLL/HLA-A∗0201, VLD/HLA-A∗0201, and RMF/HLA-A∗0201

CD8αα HLA-A∗0201 SLLQHLIGL HLA-A∗0201 VLDGLDVLL HLA-A∗0201 RMFPNAPYL Average KD
CD8αα WT KD = 100.5 μM KD = 99.2 μM KD = 193.0 μM KD = 131 μM
CD8αα S53G KD = 80.3 μM KD = 77.6 μM KD = 171.0 μM KD = 109.6 μM
CD8αα S53N KD = 34.5 μM KD = 34.0 μM KD = 76.3 μM KD = 48.2 μM