Fig. 1.

Mapping the barriers identified, separated horizontally, onto their position in the clinical translational pipeline, shown in the vertical direction. The translational pipeline is divided according to phases of discovery, validation and qualification, as defined previously [36]. Each of the thematic groupings of barriers (left to right: clinical adoption, standards development, test objects and methods, and data management) are explained in more detail in the text and form the basis of the output roadmaps.