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. 2023 Jun 19;14:281–302. doi: 10.1016/j.aninu.2023.06.002

Table 13.

Correlation between biochemical parameters, growth indices and metabolites in negative mode.

Item Villus height V:C ratio Nrf2 HO-1 CAT-P SOD-J MDA-J ROS ADG F:G ratio
(2S,3S,4S,5R,6R)-6-[[(3S,4S,6aR,6bS,8aR,9R,12aS,14bR)-9-hydroxy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-5-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxyoxane-2-carboxylic acid r = −0.66, P = 0.02 r = 0.76, P < 0.01 r = −0.72, P = 0.01 r = 0.69,
P = 0.01
Pimelic acid r = −0.65, P = 0.02 r = 0.62, P = 0.03
N-Acetyl-D-galactosamine 4-sulfate r = 0.62, P = 0.03 r = 0.71, P = 0.01
N-Gluconyl ethanolamine phosphate r = 0.64, P = 0.02 r = 0.65, P = 0.02 r = 0.85, P < 0.01 r = 0.64, P = 0.03 r = 0.72, P = 0.01 r = −0.76, P < 0.01 r = −0.79, P < 0.01 r = 0.79, P < 0.01 r = −0.78, P < 0.01
N-(2-morpholinoethyl)-4-(1H-pyrazol-1-yl)benzamide r = −0.62, P = 0.03
(−)-Stercobilin r = −0.78, P < 0.01 r = −0.68, P = 0.01 r = 0.75, P = 0.01
Methyl (9alpha,11alpha,13E,15S)-11,15-diacetoxy-9-hydroxyprost-13-en-1-oate r = 0.75, P = 0.01 r = 0.80, P < 0.01
8-[(2-Aminoethyl)sulfanyl]-1,3-dimethyl-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one r = −0.75, P < 0.01
Pantoyltaurine r = −0.74, P = 0.01 r = −0.60, P = 0.04
Mephenesin r = −0.77, P < 0.01 r = −0.63, P = 0.03

V:C ratio = villus height to crypt depth ratio; Nrf2 = nuclear factor erythroid 2-related factor 2; HO-1 = heme oxygenase 1; CAT-P = plasma catalase; SOD-J = jejunal superoxidase; MDA-J = jejunal malondialdehyde; ROS = reactive oxygen species.