Table 1.
Patient characteristics (N = 84).
| Characteristic | Value |
|---|---|
| Sex, n (%) | |
| Male | 32 (38.1) |
| Female | 52 (61.9) |
| Diagnostic method, n (%) | |
| Bronchoscopy | 60 (71.4) |
| Sputum | 24 (28.6) |
| Radiographic features, n (%) | |
| NB type | 78 (92.9) |
| FC type | 6 (7.1) |
| Age (years), mean ± SD | 66.8 ± 10.4 |
| Body mass index (kg/m2), median ± SD | 19.7 ± 2.6 |
| Smoking status Current + former smoker, n (%) | 32 (38.0) |
| Underlying disease, n (%) | |
| Cancer | 25 (29.8) |
| Tuberculosis | 8 (9.5) |
| COPD | 7 (8.3) |
| Diabetes mellitus | 7 (8.3) |
| Sinusitis | 6 (7.1) |
| Collagen disease | 11 (13.1) |
| Use of immunosuppressant, n (%) | 15 (17.9) |
| Blood tests | |
| White blood cells (/μL), mean ± SD | 6092.8 ± 2181.7 |
| Neutrophil, mean ± SD | 4061.1 ± 2056.0 |
| C reactive protein (mg/dL), mean ± SD | 0.5 ± 1.7 |
| KL-6 (IU/L), mean ± SD | 300.7 ± 177.1 |
| Alb (g/dL), mean ± SD | 4.1 ± 0.4 |
| Anti-GPL-core IgA antibody positive, n (%) | 36 (64.3) |
| IGRA positive, n (%) | 6 (12.2) |
| Pulmonary function | |
| VC (L), mean ± SD | 3.4 ± 3.0 |
| %VC (%), mean ± SD | 100.7 ± 14.7 |
| FVC (L), mean ± SD | 2.8 ± 2.6 |
| %FVC (%), mean ± SD | 99.1 ± 14.2 |
| FEV1 (L), mean ± SD | 2.0 ± 0.5 |
| %FEV1 (%), mean ± SD | 101.2 ± 20.2 |
| FEV1% (G) (%), mean ± SD | 74.6 ± 10.9 |
| Peak Flow (L/min), mean ± SD | 5.7 ± 1.5 |
| DLCO (mL/min/mmHg), mean ± SD | 19.1 ± 17.7 |
| DLCO/VA (mL/min/mmHg/L), mean ± SD | 6.6 ± 12.9 |
| Species isolated, n (%) | |
| Mycobacterium avium | 66 (78.6) |
| Mycobacterium intracellulare | 17 (20.2) |
| Unidentified species | 1 (1.2) |
| Treatment with a macrolide-containing multidrug regimen, n (%) | 43 (51.2) |
Alb, albumin; COPD, chronic obstructive pulmonary disease; DLCO, diffusing capacity for carbon monoxide; FC, fibrocavitary; FEV1, forced expiratory volume in 1 s; FEV1%(G), Gänsler's FEV1% (= FEV1/VC x 100); FVC, forced vital capacity; GPL, glycopeptidolipid; IGRA, interferon-gamma release assay; KL-6, Krebs von den Lungen; NB, nodular/bronchiectasis; SD, standard deviation; VA, alveolar ventilation; VC, vital capacity.