Table 2.
Criteria used for the classification of the evidence.
| Class |
|||||
|---|---|---|---|---|---|
| Convincing (Class I) | Highly suggestive (Class II) | Suggestive (Class III) | Weak (Class IV) | Not significant (Class ns) | |
| Criteria | number ADHD cases strictly >500 | number of ADHD cases >350 | number of ADHD cases >200 | – | – |
| p-value was strictly <0.001 | p-value was strictly <0.001 | p-value was strictly <0.001 | p-value was strictly <0.05 | p-value was ≥0.05 | |
| Heterogeneity (Iˆ2) < 50% | largest study found statistically significant effects | – | – | – | |
| 95% PI excluded the null | – | – | – | – | |
| no detection of small study effect | – | – | – | – | |
| low risk of bias for >75% participants | low risk of bias for >50% participants | – | – | – | |
| met all MASTAR-2 critical > methodological criteria (5/5) | met all AMSTAR-2 critical methodological criteria (4/5) | – | – | – | |
Abbreviations: ADHD, attention-deficit/hyperactivity disorder; AMSTAR 2, A Measurement Tool to Assess Systematic Reviews 2; CI, confidence interval; PI, prediction interval