Table 3.
KEGG pathway enrichment analysis.
| ID | Description | Gene Ratio | Bg Ratio | P value | p. adjust | Q value |
|---|---|---|---|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | 13/47 | 354/8108 | 6.15E-08 | 1.08E-05 | 7.38E-06 |
| hsa04510 | Focal adhesion | 9/47 | 201/8108 | 1.78E-06 | 0.000156783 | 0.000106897 |
| hsa04512 | ECM-receptor interaction | 6/47 | 88/8108 | 1.03E-05 | 0.000606736 | 0.000413683 |
| hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 6/47 | 100/8108 | 2.16E-05 | 0.000864446 | 0.000589395 |
| hsa00140 | Steroid hormone biosynthesis | 5/47 | 61/8108 | 2.46E-05 | 0.000864446 | 0.000589395 |
| hsa05222 | Small cell lung cancer | 5/47 | 92/8108 | 0.000177551 | 0.005101481 | 0.003478283 |
| hsa04913 | Ovarian steroidogenesis | 4/47 | 51/8108 | 0.000202900 | 0.005101481 | 0.003478283 |
| hsa04010 | MAPK signaling pathway | 8/47 | 294/8108 | 0.000248934 | 0.005476545 | 0.003734008 |
| hsa01521 | EGFR tyrosine kinase inhibitor resistance | 4/47 | 79/8108 | 0.001083577 | 0.021189959 | 0.014447699 |
| hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 4/47 | 89/8108 | 0.001688007 | 0.028011339 | 0.019098640 |
| hsa04658 | Th1 and Th2 cell differentiation | 4/47 | 92/8108 | 0.001907410 | 0.028011339 | 0.019098640 |
| hsa04657 | IL-17 signaling pathway | 4/47 | 94/8108 | 0.002064218 | 0.028011339 | 0.019098640 |
| hsa05171 | Coronavirus disease - COVID-19 | 6/47 | 232/8108 | 0.002069019 | 0.028011339 | 0.019098640 |
| hsa01522 | Endocrine resistance | 4/47 | 98/8108 | 0.002404233 | 0.028797784 | 0.019634852 |
| hsa04020 | Calcium signaling pathway | 6/47 | 240/8108 | 0.002454357 | 0.028797784 | 0.019634852 |
| hsa04660 | T cell receptor signaling pathway | 4/47 | 104/8108 | 0.002983900 | 0.032333384 | 0.022045489 |
| hsa04928 | Parathyroid hormone synthesis, secretion and action | 4/47 | 106/8108 | 0.003196652 | 0.032333384 | 0.022045489 |
| hsa04659 | Th17 cell differentiation | 4/47 | 107/8108 | 0.003306823 | 0.032333384 | 0.022045489 |
| hsa05145 | Toxoplasmosis | 4/47 | 112/8108 | 0.003896789 | 0.036096573 | 0.024611300 |