Table 1.
Antiviral efficacy of tested copolymers. The table shows CC50, IC50, and SI obtained for the SARS-CoV-2 and Vero cells. *data adopted from the previous study [24].
| Polymers | CC50* μg/ml (μM) |
IC50 μg/ml (μM) |
SI |
|---|---|---|---|
| PAMPS75-b-PAaU39 | 2.4 × 104 (8.9 × 101) | 1.9 × 10−2 (7.1 × 10−4) | 1.3 × 105 |
| PAMPS75-b-PAaU28 | 2.4 × 104 (1 × 102) | 5.4 × 10−2 (2.3 × 10−3) | 4.5 × 104 |
| PAMPS75-b-PAaU12 | 2.9 × 104 (1.5 × 102) | 2.1 × 10−1 (1.1 × 10−2) | 1.4 × 104 |
| PAMPS75-b-PAaU3 | 4.1 × 104 (2.5 × 102) | 1.1 (6.8 × 10−2) | 3.6 × 103 |
| P(AMPS50-co-AaU50) | 3.2 × 104 (1.3 × 102) | 1.8 × 10−1 (7.4 × 10−3) | 1.8 × 104 |