Table 3.
Deterioration of participants during study—within people differences. Values are means (SDs) unless stated otherwise
| Baseline (n=1254) | Two years (n=1254) | Change (95% CI) | P value | |
|---|---|---|---|---|
| No (%) in stand-up group: | ||||
| 1, no problems | 606 (48.3) | 469 (37.4) | <0.001 | |
| 2, without holding on | 242 (19.3) | 196 (15.6) | ||
| 3, unable or had to hold on | 391 (31.2) | 576 (46.0) | ||
| Dot in square best hand score | 47.6 (21.9) | 45.6 (21.1) | −2.6 (−3.7 to −1.5) | <0.001 |
| Euroqol tariff* | 0.47 (0.35) | 0.38 (0.35) | −0.10 (−0.12 to −0.08) | <0.001 |
| PDQ-39†: | ||||
| Mobility | 49.9 (33.4) | 60.5 (32.3) | 11.7 (10.2 to 13.1) | <0.001 |
| Activities of daily living | 42.2 (28.4) | 52.1 (29.2) | 10.8 (9.5 to 12.1) | <0.001 |
| Emotional wellbeing | 31.2 (23.8) | 34.6 (25.2) | 4.1 (2.9 to 5.3) | <0.001 |
| Stigma | 29.4 (27.9) | 30.7 (28.0) | 1.7 (0.4 to 3.1) | 0.013 |
| Social support | 11.6 (18.8) | 15.0 (21.5) | 3.5 (2.0 to 4.9) | <0.001 |
| Cognition | 34.8 (22.7) | 38.7 (23.8) | 4.8 (3.7 to 5.9) | <0.001 |
| Communication | 22.5 (22.8) | 28.6 (24.7) | 6.8 (5.6 to 7.9) | <0.001 |
| Bodily discomfort | 43.1 (25.5) | 44.6 (25.0) | 1.7 (0.4 to 3.0) | 0.011 |
*
High score good.
†
High score bad.