Table IV.
Comparison of PD-L1 expression, MMR status, sex, age, BMI, smoking history, alcohol consumption, liver and peritoneal metastasis between responding and non-responding patients.
| Variable | n | Responding group | Non-responding group | χ2 | P-value |
|---|---|---|---|---|---|
| Sex | |||||
| Female | 60 | 25 (36.8) | 35 (27.6) | 1.762 | 0.184 |
| Male | 135 | 43 (63.2) | 92 (72.4) | ||
| Age, years | |||||
| <65 | 120 | 45 (66.2) | 75 (59.1) | 0.949 | 0.330 |
| ≥65 | 75 | 23 (33.8) | 52 (40.9) | ||
| BMI, kg/m2 | |||||
| <18.5 | 59 | 23 (33.8) | 36 (28.3) | 0.630 | 0.428 |
| ≥18.5 | 136 | 45 (66.2) | 91 (71.7) | ||
| Drinking history | |||||
| No | 159 | 58 (85.3) | 101 (79.5) | 0.978 | 0.323 |
| Yes | 36 | 10 (14.7) | 26 (20.5) | ||
| Smoking history | |||||
| No | 126 | 46 (67.6) | 80 (63.0) | 0.420 | 0.517 |
| Yes | 69 | 22 (32.4) | 47 (37.0) | ||
| Liver metastasis | |||||
| No | 112 | 37 (54.4) | 75 (59.1) | 0.391 | 0.531 |
| Yes | 83 | 31 (45.6) | 52 (40.9) | ||
| Peritoneal metastasis | |||||
| No | 152 | 57 (83.8) | 95 (74.8) | 2.096 | 0.148 |
| Yes | 43 | 11 (16.2) | 32 (25.2) | ||
| PD-L1 expression, CPS | |||||
| <5 | 105 | 19 (27.9) | 86 (67.7) | 28.193 | <0.001 |
| ≥5 | 90 | 49 (72.1) | 41 (32.3) | ||
| MMR status | |||||
| pMMR | 178 | 57 (83.8) | 121 (95.3) | 7.299 | 0.007 |
| dMMR | 17 | 11 (16.2) | 6 (4.7) |
Data are presented as n (%). BMI, body mass index; PD-L1, programmed cell death ligand-1; CPS, combined positive score; MMR, mismatch repair; dMMR, MMR deficient; pMMR, MMR proficient.