Table V.
Variable | PFS time (95% CI), months | Log-rank | P-value |
---|---|---|---|
Age, years | 0.141 | 0.707 | |
<65 | 4.00 (3.82–4.18) | ||
≥65 | 4.00 (3.78–4.2) | ||
Sex | 2.620 | 0.106 | |
Female | 4.10 (3.68–4.52) | ||
Male | 3.90 (3.73–4.07) | ||
BMI, kg/m2 | 0.075 | 0.784 | |
<18.5 | 3.90 (3.60–4.20) | ||
≥18.5 | 4.00 (3.85–4.15) | ||
Smoking history | 0.258 | 0.612 | |
No | 4.00 (3.79–4.21) | ||
Yes | 3.90 (3.63–4.17) | ||
Drinking history | 0.110 | 0.740 | |
No | 4.00 (3.82–4.18) | ||
Yes | 3.90 (3.55–4.25) | ||
Liver metastasis | 0.036 | 0.850 | |
No | 3.90 (3.68–4.12) | ||
Yes | 4.00 (3.80–4.20) | ||
Peritoneal metastasis | 0.011 | 0.915 | |
No | 3.90 (3.72–4.08) | ||
Yes | 4.00 (3.79–4.21) | ||
PD-L1 expression, CPS | 7.220 | 0.007 | |
<5 | 3.80 (3.68–3.93) | ||
≥5 | 4.40 (4.04–4.76) | ||
MMR status | 16.475 | <0.001 | |
pMMR | 3.90 (3.76–4.05) | ||
dMMR | 9.20 (3.15–15.25) | ||
PNI | 15.936 | <0.001 | |
Low | 3.60 (3.37–3.83) | ||
High | 4.40 (4.12–4.68) | ||
ALI | 5.201 | 0.023 | |
Low | 3.80 (3.59–4.01) | ||
High | 4.00 (3.82–4.18) | ||
AGR | 18.915 | <0.001 | |
Low | 3.80 (3.39–4.21) | ||
High | 4.20 (3.65–4.75) |
PFS, progression-free survival; CI, confidence interval; BMI, body mass index; PD-L1, programmed cell death ligand-1; CPS, combined positive score; MMR, mismatch repair; dMMR, MMR deficient; pMMR, MMR proficient; PNI, prognostic nutritional index; ALI, advanced lung cancer inflammation index; AGR, albumin-globulin ratio.