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. 2023 Aug 2;14:1195647. doi: 10.3389/fendo.2023.1195647

Table 1.

Characteristics of participants grouped with or without diabetic retinopathy.

Non-DR DR p-value
N = 535 N = 302
Age, years 62.90 ± 10.55 63.88 ± 10.45 0.193
Sex, % 0.036
Male 47.10 54.64 NA
Female 52.90 45.36 NA
Race, % 0.069
Non-Hispanic White 42.24 35.76 NA
Non-Hispanic Black 26.36 35.43 NA
Mexican American 19.44 19.21 NA
Other Hispanic 8.79 7.62 NA
Other 3.18 1.99 NA
Education, % 0.257
Less than high school 19.07 23.84 NA
High school 45.42 43.38 NA
More than high school 35.51 32.78 NA
Poverty income ratio 2.36 ± 1.48 2.38 ± 1.40 0.848
Smoked at least 100 cigarettes in life, % 0.673
Yes 53.83 52.32 NA
No 46.17 47.68 NA
Drinker, % 56.07 54.97 0.757
Hypertension, % 0.770
Yes 60.56 61.59 NA
No 39.44 38.41 NA
Duration of diabetes, years 8.35 ± 9.98 15.62 ± 11.26 <0.001
Insulin therapy, % 13.83 42.72 <0.001
Body mass index, kg/m2 32.39 ± 7.10 31.55 ± 6.64 0.091
Waist circumference, cm 109.07 ± 14.79 107.67 ± 14.49 0.187
Total cholesterol (mmol/L, mean ± SD) 4.82 ± 1.21 4.83 ± 1.21 0.910
Triglyceride (mmol/L, mean ± SD) 1.96 ± 1.06 1.96 ± 1.09 0.980
HDL (mmol/L, mean ± SD) 1.26 ± 0.36 1.28 ± 0.37 0.378
LDL (mmol/L, mean ± SD) 2.60 ± 0.65 2.61 ± 0.67 0.791
HbA1C, % 6.97 ± 1.53 7.95 ± 1.76 <0.001
Hemoglobin (g/dL, mean ± SD) 13.85 ± 1.51 13.62 ± 1.70 0.047
Retinopathy severity, %
Mild NPR NA 64.9 NA
Moderate-to-severe NPR NA 25.8 NA
Proliferative retinopathy NA 9.3 NA

Mean ± SD for continuous variables: the P-value was calculated by the linear regression model.

(%) for categorical variables: the P-value was calculated by the chi-square test.

HbA1c, glycated hemoglobin; NPR, non-proliferative retinopathy; HDL, high-density lipoprotein; LDL, low-density lipoprotein; DR, diabetic retinopathy.