TABLE 1.

Patient characteristics and distribution of samples across analysis^a

Parameter	Patient data	Data by test
		16S rRNA gene sequencing	Flow cytometry analysis	Gene expression analysis	IHC analysis
Sex
Male	71	58	50	37	43
Female	24	17	13	13	19
Total samples	95	75	63	50	62
Age (mean ± SD)	48 ± 12	50 ± 11	51 ± 9	52 ± 10	51 ± 13
Group of samples
Cancer	69	60	40 (PBMCs), 22 (TILs)	40	48
Precancer	15	15	12	10	14
Healthy control	11		11
Localization
Buccal mucosa	38	33	24	20	21
Tongue	13	11	10	9	8
Upper and lower alveolus	18	16	6	11	19
T stage
I	15	15	9	10	11
II	15	15	9	10	15
III	15	15	6	10	11
IV	15	15	7	10	11
NA	09		9
N stage
Node positive	25	25	12	12	31
Node negative	35	35	19	28	17
NA	09

^aValues are presented as number of patients unless otherwise indicated.