TABLE 3.
Comparison of resistance mechanisms between exoU-positive and exoU-negative INS-PA isolatesa
| Resistance mechanisms | Value for isolates that were (n = 182): |
P value | |||
|---|---|---|---|---|---|
|
exoU positive (n = 46) |
exoU negative (n = 136) |
||||
| No. | % | No. | % | ||
| OXA-50 + PDC | 4 | 8.7 | 34 | 25.0 | 0.019 |
| OXA-50 + PDC + efflux | 3 | 6.5 | 8 | 5.9 | 0.875 |
| OXA-50 + PDC + efflux + ampC | 0 | 0.0 | 6 | 4.4 | 0.332 |
| OXA-50 + PDC + efflux + oprD | 6 | 13.0 | 22 | 16.2 | 0.661 |
| OXA-50 + PDC + MBL + efflux + oprD | 1 | 2.2 | 0 | 0.0 | 0.568 |
| OXA-50 + PDC + oprD | 7 | 15.2 | 27 | 19.9 | 0.486 |
| OXA-50 + PDC + oprD + ampC | 0 | 0.0 | 13 | 9.6 | 0.065 |
| OXA-50 + PDC + ESBL + OprD | 0 | 0.0 | 1 | 0.7 | 1.000 |
| OXA-50 + PDC + ampC | 0 | 0.0 | 5 | 3.7 | 0.425 |
| OXA-50 + PDC + efflux + ampC + oprD | 3 | 6.5 | 10 | 7.4 | 0.850 |
| OXA-50 + PDC + class A carbapenemase + efflux + ampC + oprD | 1 | 2.2 | 0 | 0.0 | 0.568 |
| OXA-50 + PDC + MBL + ESBL + oprD | 0 | 0.0 | 1 | 0.7 | 1.000 |
| OXA-50 + PDC + PBP3 | 0 | 0.0 | 1 | 0.7 | 1.000 |
| OXA-50 + PDC + oprD + PBP3 | 1 | 2.2 | 0 | 0.0 | 0.568 |
| OXA-50 + PDC + oprD + PBP3 + efflux | 2 | 4.3 | 0 | 0.0 | 0.104 |
| OXA-50 + PDC + OXA ESBL + ESBL | 1 | 2.2 | 0 | 0.0 | 0.568 |
| OXA-50 + PDC + class A carbapenemase + efflux + PBP3 + oprD | 10 | 21.7 | 0 | 0.0 | <0.001 |
| OXA-50 + PDC + class A carbapenemase + efflux + oprD | 5 | 10.9 | 0 | 0.0 | 0.001 |
| OXA-50 + PDC + class A carbapenemase | 0 | 0.0 | 1 | 0.7 | 1.000 |
| OXA-50 + PDC + MBL + OXA ESBL + PBP3 + OprD + efflux | 0 | 0.0 | 4 | 2.9 | 0.552 |
| OXA-50 + PDC + OXA ESBL + ESBL + oprD | 2 | 4.3 | 2 | 1.5 | 0.569 |
| OXA-50 + PDC + OXA ESBL + ESBL + oprD + efflux | 0 | 0.0 | 1 | 0.7 | 1.000 |
a
INS-PA, imipenem-nonsusceptible Pseudomonas aeruginosa.