Table 1. Hazard ratio of substance use disorders difference in BZD cohort versus the control cohort.
| BZD Cohort n (risk%) |
Control Cohort n (risk%) |
Hazard Ratio (95% Cl) |
P value | |
|---|---|---|---|---|
| Substance Use Disorders* | 26,569 (4.2) | 11,976 (1.9) | 2.20 (2.16- 2.25) | <0.001 |
| Sedative/hypnotic/anxiolytic related disorders | 656 (0.1) | 152 (0.0) | 4.26 (3.57- 5.09) | <0.001 |
| Alcohol Related Disorder | 5,749 (0.9) | 2,064 (0.3) | 2.74 (2.61-2.88) | <0.001 |
| Opioid Related Disorder | 2,807 (0.4) | 815 (0.1) | 3.38 (3.13-3.66) | <0.001 |
| Stimulant Related Disorder | 1,658 (0.3) | 551 (0.1) | 2.94 (2.67- 3.24) | <0.001 |
| Cannabis Related Disorder | 3,376 (0.5) | 970 (0.2) | 3.41 (3.17- 3.66) | <0.001 |
*
Substance use disorders was defined as Mental and behavioral disorders due to psychoactive substance use (ICD-10-CM: F10-F19).