Table 1.

Demographic and clinical features of MS women categorized in relation to menopausal status.

	MS women (147) (age range: 45–55 ys)
	Non-menopausal MS women (63)	Menopausal MS women (84)
Age (mean ± sd) years	46.1 ± 3.1	52.6 ± 3.2**
MS duration (mean ± sd) years	15.5 ± 6.3	18.2 ± 8.7*
EDSS score	3.3 ± 1.8	3.4 ± 2.1
Age at Menopause onset (mean ± sd) years	NA	48.5 ± 4.3
Follow-up post menopause (mean ± sd) years	NA	4.2 ± 3.5
Use of II° line DMTs	15 (23.8%)	15 (17.8%)*

^*p value: <0.05; ^***p value: <0.005. Chi-square and independent-samples t-tests were used to compare demographic and clinical variables between the two groups.