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. 2023 Aug 3;13:1112229. doi: 10.3389/fcimb.2023.1112229

Table 1.

The top 20 most cited studies.

Title First author Corresponding author Year Journal IF Total citations
RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak Liangjun Chen Yingle Liu, Ke Lan, Mang Shi, Yirong Li, Yu Chen 2020 EMERG MICROBES INFEC 19.568 344
Microbiological Diagnostic Performance of Metagenomic Next-generation Sequencing When Applied to Clinical Practice Miao Qing Bijie Hu 2018 CLIN INFECT DIS 20.999 267
Understanding the Promises and Hurdles of Metagenomic Next-Generation Sequencing as a Diagnostic Tool for Infectious Diseases Simner PJ Simner PJ 2018 CLIN INFECT DIS 20.999 254
Next-generation sequencing and metagenomic analysis: a universal diagnostic tool in plant virology Adams IP Adams IP 2009 MOL PLANT PATHOL 5.520 244
Validation of Metagenomic Next-Generation Sequencing Tests for Universal Pathogen Detection Schlaberg R Schlaberg R 2017 ARCH PATHOL LAB MED 5.686 239
Next generation sequencing and bioinformatic bottlenecks: the current state of metagenomic data analysis Scholz MB Chain PS 2012 CURR OPIN BIOTECH 10.279 213
An ensemble strategy that significantly improves de novo assembly of microbial genomes from metagenomic next-generation sequencing data Xutao Deng Xutao Deng 2015 NUCLEIC ACIDS RES 19.190 168
Assessment of Metagenomic Assembly Using Simulated Next Generation Sequencing Data Mende DR Bork P 2012 PLOS ONE 3.752 148
Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing Wilson MR Wilson MR 2018 JAMA NEUROL 29.907 145
Comparison of three next-generation sequencing platforms for metagenomic sequencing and identification of pathogens in blood Frey KG Bishop-Lilly KA 2014 BMC GENOMICS 4.547 119
Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids Wei GU C.Y. Chiu 2021 NAT MED 87.241 116
Detection of Pulmonary Infectious Pathogens From Lung Biopsy Tissues by Metagenomic Next-Generation Sequencing Henan Li Hui Wang 2018 FRONT CELL INFECT MI 6.073 92
Coinfections of Zika and Chikungunya Viruses in Bahia, Brazil, Identified by Metagenomic Next-Generation Sequencing Sardi SI C.Y. Chiu 2016 J CLIN MICROBIOL 11.677 83
mNGS in clinical microbiology laboratories: on the road to maturity Dongsheng Han Jinming Li; Rui Zhang 2019 CRIT REV MICROBIOL 7.391 67
Rapid Metagenomic Next-Generation Sequencing during an Investigation of Hospital-Acquired Human Parainfluenza Virus 3 Infections Greninger AL Greninger AL 2017 J CLIN MICROBIOL 11.677 63
Neurobrucellosis: Unexpected Answer From Metagenomic Next-Generation Sequencing Mongkolrattanothai K C.Y. Chiu 2017 J PEDIATR INFECT DIS 5.235 60
Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort Study Hogan CA Banaei N 2021 CLIN INFECT DIS 20.999 58
Metagenomic next-generation sequencing for mixed pulmonary infection diagnosis Jiahui Wang Jing Feng 2019 BMC PULM MED 3.320 57
Metagenomic Next-Generation Sequencing of Nasopharyngeal Specimens Collected from Confirmed and Suspect COVID-19 Patients Mostafa HH Simner PJ 2020 MBIO 7.786 57
Viral Surveillance in Serum Samples From Patients With Acute Liver Failure By Metagenomic Next-Generation Sequencing Somasekar S C.Y. Chiu 2017 CLIN INFECT DIS 20.999 54