Table 8. Class-based results comparison for the best, mean, standard deviation, median, and worst of class-based performance based on the GA-CNN, LCBO-CNN, MVO-CNN, SBO-CNN, WOA-CNN, and EOSA-CNN hybrid algorithms and as compared with the basic CNN architecture.

Measure	Metric	GA-CNN	LCBO-CNN	MVO-CNN	SBO-CNN	WOA-CNN	EOSA-CNN	CNN
Sensitivity
Normal	Best	0.8654	0.9368	0.875	0.9712	0.9135	0.9231	0.7115
	Mean	0.75772	0.81814	0.81156	0.8154	0.78464	0.90	0.67306
	STD	0.0791	0.14166	0.06252	0.10164	0.13072	0.04171	0.02451
	Median	0.7308	0.8558	0.8077	0.7596	0.75	0.9231	0.6635
	Worst	0.6635	0.5962	0.7212	0.7308	0.6058	0.8269	0.6538
Benign	Best	0.63333	0.76667	0.66667	0.53333	0.4	0.36667	0.53333
	Mean	0.42	0.41333	0.38665	0.34667	0.34666	0.24	0.48666
	STD	0.15741	0.21551	0.18349	0.14259	0.06912	0.10382	0.06498
	Median	0.36667	0.36667	0.3333	0.3333	0.36667	0.26667	0.53333
	Worst	0.26667	0.20	0.16667	0.16667	0.23333	0.13333	0.4
Malignant	Best	0.9	0.9214	0.8429	0.9071	0.9214	0.9071	0.85
	Mean	0.85858	0.82858	0.82286	0.83856	0.86856	0.86712	0.83858
	STD	0.03655	0.07676	0.01706	0.0543	0.05613	0.04213	0.01082
	Median	0.8643	0.8143	0.8214	0.8429	0.8786	0.8643	0.8357
	Worst	0.8143	0.7429	0.8	0.7571	0.7786	0.8071	0.8286
Specificity
Normal	Best	0.8941	0.9588	0.8882	0.9059	0.8824	0.8882	0.8529
	Mean	0.85296	0.81882	0.81762	0.80234	0.83412	0.81292	0.83292
	STD	0.043	0.09532	0.04138	0.06625	0.05712	0.04893	0.01535
	Median	0.8647	0.7941	0.8059	0.7882	0.8588	0.7941	0.8353
	Worst	0.7824	0.7059	0.7882	0.7412	0.7588	0.7588	0.8176
Benign	Best	0.92623	0.93443	0.91803	0.97131	0.94262	0.97951	0.84836
	Mean	0.86803	0.8872	0.88359	0.89342	0.88443	0.93689	0.83361
	STD	0.04351	0.05474	0.03602	0.05011	0.05636	0.03169	0.00943
	Median	0.86066	0.90164	0.8893	0.877	0.877	0.93443	0.83197
	Worst	0.82377	0.80328	0.84426	0.84016	0.8115	0.89344	0.8238
Malignant	Best	0.985	1	1	1	0.9851	1	0.9851
	Mean	0.9612	0.98358	0.97462	0.98656	0.97016	0.96568	0.9776
	STD	0.01932	0.01435	0.01946	0.00973	0.01903	0.03192	0.0053
	Median	0.9552	0.9851	0.9701	0.9851	0.9776	0.9478	0.9776
	Worst	0.9403	0.9627	0.9478	0.9776	0.9403	0.9328	0.9701
Precision
Normal	Best	0.8065	0.8986	0.8155	0.8261	0.7959	0.819	0.7396
	Mean	0.76264	0.74924	0.73322	0.72264	0.7482	0.74984	0.71148
	STD	0.03492	0.09224	0.04791	0.06092	0.03739	0.04546	0.02475
	Median	0.7667	0.7177	0.7165	0.7063	0.759	0.7328	0.7113
	Worst	0.7087	0.6599	0.6949	0.6716	0.6985	0.7007	0.6869
Benign	Best	0.30769	0.40741	0.35088	0.41667	0.42308	0.47826	0.30189
	Mean	0.28194	0.31394	0.28188	0.30389	0.29414	0.339	0.26439
	STD	0.04213	0.07393	0.06118	0.07401	0.09156	0.12445	0.0328
	Median	0.30556	0.32394	0.2703	0.29091	0.2857	0.33333	0.27586
	Worst	0.2093	0.21429	0.2	0.2105	0.1786	0.18182	0.2182
Malignant	Best	0.9844	1	1	1	0.984	1	0.9835
	Mean	0.9585	0.98232	0.97164	0.98464	0.96884	0.9652	0.97508
	STD	0.02039	0.01412	0.02146	0.01097	0.018	0.03218	0.00594
	Median	0.9508	0.9818	0.9672	0.9815	0.9732	0.9478	0.975
	Worst	0.9394	0.9627	0.9421	0.9748	0.9407	0.9338	0.9667
Recall
Normal	Best	0.8654	0.9368	0.875	0.9712	0.9135	0.9231	0.7115
	Mean	0.75772	0.81814	0.81156	0.8154	0.78464	0.90	0.67306
	STD	0.0791	0.14166	0.06252	0.10164	0.13072	0.04171	0.02451
	Median	0.7308	0.8558	0.8077	0.7596	0.75	0.9231	0.6635
	Worst	0.6635	0.5962	0.7212	0.7308	0.6058	0.8269	0.6538
Benign	Best	0.63333	0.76667	0.66667	0.53333	0.4	0.36667	0.53333
	Mean	0.42	0.41333	0.38665	0.34667	0.34666	0.24	0.48666
	STD	0.15741	0.21551	0.18349	0.14259	0.06912	0.10382	0.06498
	Median	0.36667	0.36667	0.3333	0.3333	0.36667	0.26667	0.53333
	Worst	0.26667	0.2	0.16667	0.16667	0.23333	0.13333	0.40
Malignant	Best	0.9	0.9214	0.8429	0.9071	0.9214	0.9071	0.85
	Mean	0.85858	0.82858	0.82286	0.83856	0.86856	0.86712	0.83858
	STD	0.03655	0.07676	0.01706	0.0543	0.05613	0.04213	0.01082
	Median	0.8643	0.8143	0.8214	0.8429	0.8786	0.8643	0.8357
	Worst	0.8143	0.7429	0.80	0.7571	0.7786	0.8071	0.8286
F1 score
Normal	Best	0.785	0.8128	0.8116	0.8178	0.8085	0.8384	0.722
	Mean	0.75714	0.76846	0.7691	0.76138	0.7595	0.8164	0.69172
	STD	0.02938	0.03413	0.0408	0.03759	0.05248	0.01586	0.02356
	Median	0.7614	0.7706	0.7879	0.7563	0.7723	0.817	0.6866
	Worst	0.7113	0.7168	0.7143	0.7215	0.6738	0.7967	0.67
Benign	Best	0.41304	0.45545	0.45977	0.37647	0.39286	0.41509	0.38554
	Mean	0.3293	0.34205	0.31888	0.30383	0.30819	0.26946	0.34253
	STD	0.06568	0.09716	0.09907	0.06419	0.06051	0.09936	0.04303
	Median	0.33333	0.38596	0.32099	0.3226	0.3077	0.27692	0.36364
	Worst	0.24658	0.23077	0.18182	0.2353	0.2326	0.15385	0.2824
Malignant	Best	0.9403	0.9416	0.9105	0.9513	0.9416	0.9272	0.9119
	Mean	0.90558	0.897	0.89096	0.90512	0.91492	0.9125	0.90168
	STD	0.02643	0.04082	0.01476	0.03521	0.02937	0.01712	0.00829
	Median	0.9118	0.8976	0.888	0.9042	0.9236	0.9203	0.90
	Worst	0.8736	0.849	0.8736	0.8548	0.8651	0.8933	0.8923
Balanced Accuracy
Normal	Best	0.8274	0.8655	0.848	0.862	0.8508	0.8762	0.7764
	Mean	0.80532	0.81848	0.81458	0.80886	0.80936	0.85648	0.753
	STD	0.02315	0.03129	0.03384	0.03411	0.04133	0.01314	0.01856
	Median	0.8076	0.8161	0.8316	0.8033	0.8162	0.8576	0.7494
	Worst	0.77	0.7775	0.7694	0.7739	0.7441	0.841	0.7357
Benign	Best	0.72855	0.78497	0.75751	0.68675	0.6526	0.65874	0.69085
	Mean	0.64402	0.65027	0.63513	0.62007	0.61554	0.58844	0.66014
	STD	0.06144	0.08653	0.07787	0.05084	0.03404	0.04905	0.03479
	Median	0.6321	0.64929	0.6257	0.6216	0.6262	0.59672	0.6806
	Worst	0.58033	0.56721	0.54235	0.56899	0.5724	0.52978	0.6119
Malignant	Best	0.9425	0.9421	0.9179	0.9536	0.9421	0.9321	0.9175
	Mean	0.90986	0.90608	0.89874	0.91256	0.91936	0.91642	0.9081
	STD	0.02425	0.03313	0.01405	0.0302	0.02448	0.0146	0.00747
	Median	0.913	0.9071	0.8958	0.9102	0.9237	0.92	0.9067
	Worst	0.881	0.8677	0.881	0.8711	0.8781	0.8989	0.8994