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. 2023 Aug 7;19(8):e1011274. doi: 10.1371/journal.ppat.1011274

Fig 5. Summary of ZIKV viral burden at 14 dpi.

Fig 5

(A) Artistic representation of ZIKV infection in the maternal-fetal interface at 14 days post infection (dpi). Pink tissue/structure names denote that ZIKV RNA was detected via ISH or RT-qPCR. The number of cases where the tissue had ZIKV RNA detected out of the number of cases in which tissue was evaluated is indicated below each tissue name. An artistic representation of the infection of each tissue is illustrated in pink in the figure. (B) Summary of the ZIKV RNA detected via RT-qPCR. The level of ZIKV burden is summarized as high (>1000 ZIKV RNA copies/mg of tissue, medium (>100 ZIKV RNA copies/mg or mL), low (<100 copies/mg of tissue), below the limit of detection, or NA, sample not available. The theoretical limit of detection for all the tissues is 3 copies/mg. (D) Summary of ZIKV RNA detected via ISH. ZIKV RNA was noted as present (+) or absent (-) in the indicated tissues/structures. In some instances, adequate histological samples were not obtained, and could not be properly evaluated (/). (B) (C) Individual animal IDs are listed on the bottom.