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JPYZXZ reduced the number of MDSCs in tumor bearing mice. (A,B) Percentage of MDSCs (CD45+CD11b+Gr1+) in blood determined using flow cytometry. (C,D) Percentage of MDSCs (CD45+CD11b+Gr1+) in tumors determined using flow cytometry. (E) Immunofluorescence staining for DAPI (nucleus), CD11b, Gr-1, and PD-L1 in tumor tissue sections from the xenograft tumor model. Data are represented as the mean ± SEM, n = 5 mice or n = 3 independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001.
